InnateDB Protein
|
IDBP-26949.5
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
TMEM88
|
Protein Name
|
transmembrane protein 88
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000301599
|
InnateDB Gene
|
IDBG-26947 (TMEM88)
|
Protein Structure
|
|
Function |
Inhibits the Wnt/beta-catenin signaling pathway. Crucial for heart development and acts downstream of GATA factors in the pre-cardiac mesoderm to specify lineage commitment of cardiomyocyte development. {ECO:0000269PubMed:23924634}.
|
Subcellular Localization |
Cell membrane {ECO:0000269PubMed:21044957}; Multi-pass membrane protein {ECO:0000269PubMed:21044957}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|
Predicted by orthology |
Total |
1 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
|
PFAM |
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q6PEY1
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
92162
|
UniGene |
|
RefSeq |
NP_981956
|
HUGO |
HGNC:32371
|
OMIM |
|
CCDS |
CCDS11121
|
HPRD |
17438
|
IMGT |
|
EMBL |
BC057812
|
GenPept |
AAH57812
|
|
|