InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pkp3

Summary

InnateDB Protein

IDBP-269595.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pkp3

Protein Name

plakophilin 3

Synonyms

2310056L12Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000101654

InnateDB Gene

IDBG-211965 (Pkp3)

Protein Structure

UniProt Annotation

Function

May play a role in junctional plaques.

Subcellular Localization

Nucleus. Cell junction, desmosome. Note=Nuclear and associated with desmosomes.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0050839	cell adhesion molecule binding

Biological Process

GO:0002159	desmosome assembly
GO:0016337	single organismal cell-cell adhesion
GO:0090002	establishment of protein localization to plasma membrane

Cellular Component

GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0005914	spot adherens junction
GO:0030057	desmosome

Protein Structure and Domains

PDB ID

MGI:1891830

InterPro

IPR000225 Armadillo
IPR016024 Armadillo-type fold

PFAM

PF00514

PRINTS

PIRSF

SMART

SM00185

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9QY23

PhosphoSite

PhosphoSite-Q9QY23

TrEMBL

E0CY75

UniProt Splice Variant

Entrez Gene

56460

UniGene

Mm.350037

RefSeq

NP_001156396

MGI ID

MGI Symbol

Pkp3

OMIM

CCDS

CCDS52437

HPRD

IMGT

EMBL

AC109272 AF136719 BC090668 BC106141 BC139775

GenPept

AAD55892 AAH90668 AAI06142 AAI39776