InnateDB Protein
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IDBP-269795.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Gmeb1
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Protein Name
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glucocorticoid modulatory element binding protein 1
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Synonyms
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1110050A04Rik; AI256615; AI481278;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000101585
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InnateDB Gene
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IDBG-193716 (Gmeb1)
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Protein Structure
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Function |
Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus. Cytoplasm. Note=May be also cytoplasmic.
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Disease Associations |
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Tissue Specificity |
Ubiquitous. Low levels were detected in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated |
Total |
6
[view]
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Protein-Protein |
6
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
9 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2135604
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InterPro |
IPR000770
SAND domain
IPR010919
SAND domain-like
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PFAM |
PF01342
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PRINTS |
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PIRSF |
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SMART |
SM00258
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TIGRFAMs |
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Modification |
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SwissProt |
Q9JL60
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
56809
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UniGene |
Mm.103489
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RefSeq |
NP_001116464
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MGI ID |
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MGI Symbol |
Gmeb1
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OMIM |
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CCDS |
CCDS18720
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HPRD |
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IMGT |
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EMBL |
AF210433
BC046983
BX537301
CH466552
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GenPept |
AAF72874
AAH46983
CAM14478
EDL30116
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