Version 5.4
Mus musculus Protein: Wdtc1
Summary
InnateDB Protein IDBP-269879.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Wdtc1
Protein Name WD and tetratricopeptide repeats 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000101526
InnateDB Gene IDBG-194954 (Wdtc1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004857 enzyme inhibitor activity
GO:0005515 protein binding
GO:0042393 histone binding
GO:0042826 histone deacetylase binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001701 in utero embryonic development
GO:0006006 glucose metabolic process
GO:0008361 regulation of cell size
GO:0032869 cellular response to insulin stimulus
GO:0035264 multicellular organism growth
GO:0043086 negative regulation of catalytic activity
GO:0045717 negative regulation of fatty acid biosynthetic process
GO:0055082 cellular chemical homeostasis
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:2685541
InterPro IPR001680 WD40 repeat
IPR013026 Tetratricopeptide repeat-containing domain
IPR017986 WD40-repeat-containing domain
IPR019734 Tetratricopeptide repeat
PFAM PF00400
PF13174
PF13176
PF13181
PRINTS
PIRSF
SMART SM00320
SM00028
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A2AE98
UniProt Splice Variant
Entrez Gene 230796
UniGene
RefSeq
MGI ID
MGI Symbol Wdtc1
OMIM
CCDS
HPRD
IMGT
EMBL AL671882
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca