InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Myom3

Summary

InnateDB Protein

IDBP-269987.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Myom3

Protein Name

myomesin family, member 3

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000101480

InnateDB Gene

IDBG-197224 (Myom3)

Protein Structure

UniProt Annotation

Function

May link the intermediate filament cytoskeleton to the M-disk of the myofibrils in striated muscle. {ECO:0000250}.

Subcellular Localization

Cytoplasm, myofibril, sarcomere, M line {ECO:0000269PubMed:18177667}.

Disease Associations

Tissue Specificity

Mainly expressed in slow muscle, extraocular muscle and embryonic/neonatal skeletal muscle (at protein level). Expression in skeletal muscle is fiber type specific, with the highest levels in type IIA fibers (intermediate speed) and lower levels in type I fibers. {ECO:0000269PubMed:18177667}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0031430

M band

Protein Structure and Domains

PDB ID

MGI:2685280

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM

PF00041
PF01108
PF07679
PF07686
PF00047

PRINTS

PIRSF

SMART

SM00408
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

A2ABU4