Version 5.4
Mus musculus Protein: Aurkaip1
Summary
InnateDB Protein IDBP-270546.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aurkaip1
Protein Name aurora kinase A interacting protein 1
Synonyms 0610033H09Rik; Aip; Akip; MRP-S38;
Species Mus musculus
Ensembl Protein ENSMUSP00000101217
InnateDB Gene IDBG-207942 (Aurkaip1)
Protein Structure
UniProt Annotation
Function May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation.
Subcellular Localization Mitochondrion {ECO:0000250}. Nucleus.
Disease Associations
Tissue Specificity Ubiquitously expressed and especially highly expressed in heart, skeletal muscle and testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004842 ubiquitin-protein transferase activity
Biological Process
GO:0016567 protein ubiquitination
GO:0045862 positive regulation of proteolysis
Cellular Component
GO:0005634 nucleus
GO:0005680 anaphase-promoting complex
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:1913327
InterPro IPR013177 Domain of unknown function DUF1713, mitochondria
PFAM PF08213
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DCJ7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 66077
UniGene Mm.28999
RefSeq XP_006539159
MGI ID
MGI Symbol Aurkaip1
OMIM
CCDS CCDS19043
HPRD
IMGT
EMBL AK002737 AK003442 AK144719 AK166049 AL670236
GenPept BAB22317 BAB22792 BAE26030 BAE38543 CAM18389

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca