InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Psap

Summary

InnateDB Protein

IDBP-270826.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Psap

Protein Name

prosaposin

Synonyms

AI037048; SGP-1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000101105

InnateDB Gene

IDBG-154504 (Psap)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	30 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006629	lipid metabolic process
GO:0006665	sphingolipid metabolic process
GO:0019216	regulation of lipid metabolic process
GO:0043408	regulation of MAPK cascade
GO:0048589	developmental growth
GO:0060736	prostate gland growth
GO:0060742	epithelial cell differentiation involved in prostate gland development
GO:0071310	cellular response to organic substance

Cellular Component

GO:0005615	extracellular space
GO:0005739	mitochondrion
GO:0005764	lysosome
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:97783

InterPro

IPR003119 Saposin type A
IPR007856 Saposin-like type B, 1
IPR008138 Saposin-like type B, 2
IPR008139 Saposin B
IPR008373 Saposin
IPR011001 Saposin-like
IPR021165 Saposin, chordata

PFAM

PF02199
PF05184
PF03489

PRINTS

PR01797

PIRSF

PIRSF002431

SMART

SM00162
SM00741

TIGRFAMs

Post-translational Modifications

Modification

Cross-References