Version 5.4
Mus musculus Protein: Lrrtm3
Summary
InnateDB Protein IDBP-270878.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lrrtm3
Protein Name leucine rich repeat transmembrane neuronal 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000101079
InnateDB Gene IDBG-159646 (Lrrtm3)
Protein Structure
UniProt Annotation
Function May play a role in the development and maintenance of the vertebrate nervous system. Exhibits a limited synaptogenic activity in vitro, restricted to excitatory presynaptic differentiation (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in neuronal tissues. {ECO:0000269PubMed:12676565}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:1902004 positive regulation of beta-amyloid formation
Cellular Component
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0045211 postsynaptic membrane
Protein Structure and Domains
PDB ID MGI:2389177
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF01462
PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00013
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BZ81
PhosphoSite PhosphoSite-Q8BZ81
TrEMBL
UniProt Splice Variant
Entrez Gene 216028
UniGene Mm.472104
RefSeq NP_848793
MGI ID
MGI Symbol Lrrtm3
OMIM
CCDS CCDS35925
HPRD
IMGT
EMBL AK032485 AK035773 AK035858 AK035882 AK036366 AK163753 AY182029 BC113178 BC113784
GenPept AAI13179 AAI13785 AAO67550 BAC29181 BAC29214 BAC29226 BAC29398 BAE37481 BAE43281

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca