Version 5.4
Mus musculus Protein: Gas2l3
Summary
InnateDB Protein IDBP-271177.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gas2l3
Protein Name growth arrest-specific 2 like 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000100935
InnateDB Gene IDBG-184215 (Gas2l3)
Protein Structure
UniProt Annotation
Function Cytoskeletal linker protein. May promote and stabilize the formation of the actin and microtubule network (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Localizes to microtubule and actin cytoskeletons. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0008017 microtubule binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0007050 cell cycle arrest
GO:0030036 actin cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0015629 actin cytoskeleton
GO:0015630 microtubule cytoskeleton
Protein Structure and Domains
PDB ID MGI:1918780
InterPro IPR001715 Calponin homology domain
IPR003108 Growth-arrest-specific protein 2 domain
PFAM PF00307
PF02187
PRINTS
PIRSF
SMART SM00033
SM00243
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UWW6
PhosphoSite PhosphoSite-Q3UWW6
TrEMBL
UniProt Splice Variant
Entrez Gene 237436
UniGene Mm.405809
RefSeq NP_001271273
MGI ID
MGI Symbol Gas2l3
OMIM
CCDS CCDS24115
HPRD
IMGT
EMBL AK136054 AK170750
GenPept BAE22798 BAE42001

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca