Version 5.4
Homo sapiens Protein: BDP1
Summary
InnateDB Protein IDBP-27252.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BDP1
Protein Name B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000351575
InnateDB Gene IDBG-27250 (BDP1)
Protein Structure
UniProt Annotation
Function General activator of RNA polymerase III transcription. Requires for transcription from all three types of polymerase III promoters. Requires for transcription of genes with internal promoter elements and with promoter elements upstream of the initiation site. {ECO:0000269PubMed:11040218}.
Subcellular Localization Nucleus {ECO:0000269PubMed:11161782}.
Disease Associations
Tissue Specificity Isoform 2 is highly expressed in cerebellum. {ECO:0000269PubMed:11161782}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006383 transcription from RNA polymerase III promoter
GO:0010467 gene expression
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001005 SANT/Myb domain
IPR009057 Homeodomain-like
PFAM PF00249
PRINTS
PIRSF
SMART SM00717
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A6H8Y1
PhosphoSite PhosphoSite-A6H8Y1
TrEMBL
UniProt Splice Variant
Entrez Gene 55814
UniGene Hs.258272
RefSeq NP_060899
HUGO HGNC:13652
OMIM 607012
CCDS CCDS43328
HPRD 06114
IMGT
EMBL AB033067 AB051476 AC138832 AF176695 AF298151 AF298152 AJ238520 AJ278892 AJ279120 AJ279121 AJ279122 AJ279123 AJ279124 AJ279125 AJ279126 AJ279127 AJ279128 AJ279129 AJ279130 AJ279131 AJ279132 AJ279133 AJ279134 AJ279135 AJ279136 AJ279137 AJ279138 AJ279139 AJ279140 AJ279141 AJ279142 AJ279143 AJ279144 AJ279145 AJ279146 AJ279147 AJ279148 AJ279149 AJ279150 AK057871 BC032146 BC146792 BX641011 CR749229 CR749289
GenPept AAG09268 AAG30220 AAG30221 AAH32146 AAI46793 BAA86555 BAB21780 BAB71602 CAC04245 CAC17771 CAC21448 CAE46010 CAH18085 CAH18144

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca