Version 5.4
Mus musculus Protein: Skor1
Summary
InnateDB Protein IDBP-273694.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Skor1
Protein Name SKI family transcriptional corepressor 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000112312
InnateDB Gene IDBG-175143 (Skor1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003714 transcription corepressor activity
GO:0005488 binding
GO:0005515 protein binding
GO:0046332 SMAD binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
GO:0030425 dendrite
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID MGI:2443473
InterPro IPR003380 Transforming protein Ski
IPR009061 DNA binding domain, putative
IPR010919 SAND domain-like
IPR014890 c-SKI SMAD4-binding domain
PFAM PF02437
PF08782
PRINTS
PIRSF
SMART SM01046
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3YX64
UniProt Splice Variant
Entrez Gene 207667
UniGene Mm.488921
RefSeq NP_001157230
MGI ID
MGI Symbol Skor1
OMIM
CCDS CCDS52828
HPRD
IMGT
EMBL AC159821 AC160392 CH466522
GenPept EDL26035

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca