Homo sapiens Protein: PRSS53 | |||||||
---|---|---|---|---|---|---|---|
Summary | |||||||
InnateDB Protein | IDBP-27703.5 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | PRSS53 | ||||||
Protein Name | protease, serine, 53 | ||||||
Synonyms | |||||||
Species | Homo sapiens | ||||||
Ensembl Protein | ENSP00000280606 | ||||||
InnateDB Gene | IDBG-27701 (PRSS53) | ||||||
Protein Structure | |||||||
UniProt Annotation | |||||||
Function | In vitro can degrade the fibrinogen alpha chain of as well as pro-urokinase-type plasminogen activator. {ECO:0000269PubMed:16566820}. | ||||||
Subcellular Localization | Secreted {ECO:0000269PubMed:16566820}. | ||||||
Disease Associations | |||||||
Tissue Specificity | Predominantly detected in testis, liver, heart and ovary, as well as in several tumor cell lines. {ECO:0000269PubMed:16566820}. | ||||||
Comments | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||||||
Gene Ontology | |||||||
Molecular Function |
|
||||||
Biological Process |
|
||||||
Cellular Component |
|
||||||
Protein Structure and Domains | |||||||
PDB ID | |||||||
InterPro |
IPR001254
Peptidase S1 IPR001314 Peptidase S1A, chymotrypsin-type IPR009003 Trypsin-like cysteine/serine peptidase domain IPR015420 Peptidase S1A, nudel |
||||||
PFAM |
PF00089
PF09342 |
||||||
PRINTS |
PR00722
|
||||||
PIRSF | |||||||
SMART |
SM00020
|
||||||
TIGRFAMs | |||||||
Post-translational Modifications | |||||||
Modification | |||||||
Cross-References | |||||||
SwissProt | Q2L4Q9 | ||||||
PhosphoSite | PhosphoSite- | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 339105 | ||||||
UniGene | Hs.569575 | ||||||
RefSeq | NP_001034592 | ||||||
HUGO | HGNC:34407 | ||||||
OMIM | 610561 | ||||||
CCDS | CCDS42153 | ||||||
HPRD | |||||||
IMGT | |||||||
EMBL | AJ627035 | ||||||
GenPept | CAF25304 | ||||||