InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ALPK3

Summary

InnateDB Protein

IDBP-27765.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ALPK3

Protein Name

alpha-kinase 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000258888

InnateDB Gene

IDBG-27763 (ALPK3)

Protein Structure

UniProt Annotation

Function

Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation. Plays a role in cardiomyocyte differentiation (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004674	protein serine/threonine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0007507	heart development

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR004166 MHCK/EF2 kinase
IPR007110 Immunoglobulin-like domain
IPR011009 Protein kinase-like domain
IPR013098 Immunoglobulin I-set

PFAM

PF02816
PF07679

PRINTS

PIRSF

SMART

SM00408
SM00409
SM00811

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q96L96