InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: COX6A2

Summary

InnateDB Protein

IDBP-28471.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

COX6A2

Protein Name

cytochrome c oxidase subunit VIa polypeptide 2

Synonyms

COX6AH; COXVIAH;

Species

Homo sapiens

Ensembl Protein

ENSP00000287490

InnateDB Gene

IDBG-28469 (COX6A2)

Protein Structure

UniProt Annotation

Function

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subcellular Localization

Mitochondrion inner membrane.

Disease Associations

Tissue Specificity

Expressed specifically in heart and muscle. {ECO:0000269PubMed:1327966}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004129	cytochrome-c oxidase activity

Biological Process

GO:0006091	generation of precursor metabolites and energy
GO:1902600	hydrogen ion transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005751	mitochondrial respiratory chain complex IV

Protein Structure and Domains

PDB ID

InterPro

IPR001349 Cytochrome c oxidase, subunit VIa

PFAM

PF02046

PRINTS

PIRSF

PIRSF000277

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q02221

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

1339

UniGene

Hs.602232

RefSeq

NP_005196

HUGO

HGNC:2279

OMIM

602009

CCDS

CCDS10712

HPRD

03598

IMGT

EMBL

BC029818 M83308 U66875

GenPept

AAA52062 AAC51328 AAH29818