InnateDB Protein
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IDBP-2863.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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LRP10
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Protein Name
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low density lipoprotein receptor-related protein 10
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Synonyms
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LRP9; MST087;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000352601
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InnateDB Gene
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IDBG-2861 (LRP10)
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Protein Structure
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Function |
Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver (By similarity). {ECO:0000250}.
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Subcellular Localization |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Membrane, coated pit {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed in blood leukocyte, lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, skeletal muscle and heart. {ECO:0000269PubMed:11123907}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000859
CUB domain
IPR002172
Low-density lipoprotein (LDL) receptor class A repeat
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PFAM |
PF00431
PF00057
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PRINTS |
PR00261
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PIRSF |
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SMART |
SM00042
SM00192
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TIGRFAMs |
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Modification |
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SwissProt |
Q7Z4F1
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PhosphoSite |
PhosphoSite-Q7Z4F1
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TrEMBL |
Q6IAK3
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UniProt Splice Variant |
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Entrez Gene |
26020
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UniGene |
Hs.606547
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RefSeq |
NP_054764
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HUGO |
HGNC:14553
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OMIM |
609921
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CCDS |
CCDS9578
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HPRD |
14311
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IMGT |
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EMBL |
AF131760
AF172816
AF177336
AK291030
AL080164
AL834518
AY358399
BC064901
BC080648
BC088378
BC113714
BC113716
BX161500
CH471078
CR457151
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GenPept |
AAD20037
AAG17980
AAH64901
AAH80648
AAH88378
AAI13715
AAI13717
AAQ13610
AAQ88765
BAF83719
CAB45753
CAD39174
CAD61944
CAG33432
EAW66232
EAW66235
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