Version 5.4
Homo sapiens Protein: HSD17B13
Summary
InnateDB Protein IDBP-28933.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSD17B13
Protein Name hydroxysteroid (17-beta) dehydrogenase 13
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000305438
InnateDB Gene IDBG-28929 (HSD17B13)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Highly expressed in the liver. Also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis. {ECO:0000269PubMed:17311113}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016491 oxidoreductase activity
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002347 Glucose/ribitol dehydrogenase
PFAM PF00106
PRINTS PR00080
PR00081
PIRSF PIRSF000126
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7Z5P4
PhosphoSite PhosphoSite-Q7Z5P4
TrEMBL
UniProt Splice Variant
Entrez Gene 345275
UniGene Hs.284414
RefSeq NP_001129702
HUGO HGNC:18685
OMIM 612127
CCDS CCDS47097
HPRD 18023
IMGT
EMBL AB073347 AK292784 AY186249 AY186250 AY268355 AY358575 BC112303 BC112305 CH471057
GenPept AAI12304 AAI12306 AAO72313 AAO72314 AAP42289 AAQ88938 BAD38632 BAF85473 EAX05986

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca