Version 5.4
Homo sapiens Protein: MEX3D
Summary
InnateDB Protein IDBP-292613.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MEX3D
Protein Name mex-3 homolog D (C. elegans)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000384398
InnateDB Gene IDBG-14757 (MEX3D)
Protein Structure
UniProt Annotation
Function RNA binding protein, may be involved in post- transcriptional regulatory mechanisms. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. {ECO:0000250}.
Disease Associations
Tissue Specificity Ubiquitously expressed in all the cell lines and tissues tested. {ECO:0000269PubMed:17267406}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0017091 AU-rich element binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression
GO:0061157 mRNA destabilization
Cellular Component
GO:0005634 nucleus
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001841 Zinc finger, RING-type
IPR004087 K Homology domain
IPR004088 K Homology domain, type 1
PFAM PF13639
PF14634
PF00013
PF13014
PRINTS
PIRSF
SMART SM00184
SM00322
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86XN8
PhosphoSite PhosphoSite-Q86XN8
TrEMBL
UniProt Splice Variant
Entrez Gene 399664
UniGene Hs.436495
RefSeq NP_976049
HUGO HGNC:16734
OMIM 611009
CCDS CCDS32865
HPRD 15254
IMGT
EMBL AB107353 AC005943 AC027307 AF458084 AY950680 BC113384 BC113741
GenPept AAI13385 AAI13742 AAQ04763 AAY34148 BAC67658

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca