InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DNHD1

Summary

InnateDB Protein

IDBP-29286.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DNHD1

Protein Name

dynein heavy chain domain 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000254579

InnateDB Gene

IDBG-29243 (DNHD1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003777	microtubule motor activity
GO:0004176	ATP-dependent peptidase activity
GO:0004252	serine-type endopeptidase activity

Biological Process

GO:0006508	proteolysis
GO:0007018	microtubule-based movement
GO:0008152	metabolic process
GO:0016192	vesicle-mediated transport

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030286	dynein complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR004273 Dynein heavy chain domain
IPR010989 t-SNARE
IPR013602 Dynein heavy chain, domain-2
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF03028
PF08393

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q96M86

PhosphoSite

PhosphoSite-Q96M86

TrEMBL

UniProt Splice Variant

Entrez Gene

144132

UniGene

Hs.720080

RefSeq

NP_653267

HUGO

HGNC:26532

OMIM

CCDS

CCDS44532

HPRD

08137

IMGT

EMBL

AC009796 AC084337 AK057314 AK074178 AK093028 AL137619 AY358770 BC111765 BC117301 BC117303 CH471064

GenPept

AAI11766 AAI17302 AAI17304 AAQ89130 BAB71423 BAB85004 BAC04023 CAB70845 EAW68692 EAW68702