Version 5.4
Homo sapiens Protein: MEI1
Summary
InnateDB Protein IDBP-293226.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MEI1
Protein Name meiosis inhibitor 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000384115
InnateDB Gene IDBG-9397 (MEI1)
Protein Structure
UniProt Annotation
Function Required for normal meiotic chromosome synapsis. May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes (By similarity). {ECO:0000250UniProtKB:Q9D4I2}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed predominantly in testis. Weakly expressed in spleen and thymus. {ECO:0000269PubMed:16683055}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
Biological Process
GO:0007126 meiotic nuclear division
GO:0007141 male meiosis I
GO:0007276 gamete generation
GO:0007286 spermatid development
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR016024 Armadillo-type fold
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5TIA1
PhosphoSite PhosphoSite-Q5TIA1
TrEMBL
UniProt Splice Variant
Entrez Gene 150365
UniGene
RefSeq NP_689726
HUGO HGNC:28613
OMIM 608797
CCDS CCDS46718
HPRD
IMGT
EMBL AK094461 AK301435 AL021453 AL023879 AY952376 AY952377 BC025400 BC032248 BC035720 Z83840
GenPept AAH25400 AAH32248 AAH35720 AAY27427 AAY27428 BAC04361 BAH13481 CAI17919 CAI22918 CAQ09777 CAQ10977

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca