InnateDB Protein
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IDBP-293281.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GYLTL1B
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Protein Name
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glycosyltransferase-like 1B
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000385235
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InnateDB Gene
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IDBG-41317 (GYLTL1B)
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Protein Structure
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Function |
Glycosyltransferase which participates in glycosylation of alpha-dystroglycan. May carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. Has a higher activity toward alpha-dystroglycan than LARGE. {ECO:0000269PubMed:15661757, ECO:0000269PubMed:15752776}.
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Subcellular Localization |
Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Widely expressed. Expressed at high level in placenta, pancreas and kidney compared to LARGE. Not expressed in brain. {ECO:0000269PubMed:15752776, ECO:0000269PubMed:15958417}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0016757
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transferase activity, transferring glycosyl groups
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002495
Glycosyl transferase, family 8
IPR029044
Nucleotide-diphospho-sugar transferases
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PFAM |
PF01501
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8N3Y3
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PhosphoSite |
PhosphoSite-Q8N3Y3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
120071
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UniGene |
Hs.86543
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RefSeq |
NP_001287650
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HUGO |
HGNC:16522
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OMIM |
609709
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CCDS |
CCDS31473
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HPRD |
13618
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IMGT |
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EMBL |
AC068385
AF258588
AK092526
AK096021
BC037291
CH471064
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GenPept |
AAG23791
AAH37291
BAC03909
BAC04675
EAW68021
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