InnateDB Protein
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IDBP-293285.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TEF
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Protein Name
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thyrotrophic embryonic factor
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000385256
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InnateDB Gene
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IDBG-9151 (TEF)
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Protein Structure
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Function |
Transcription factor that binds to and transactivates the TSHB promoter. Binds to a minimal DNA-binding sequence 5'- [TC][AG][AG]TTA[TC][AG]-3'.
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Subcellular Localization |
Nucleus.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
11
[view]
|
Protein-Protein |
8
[view]
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Protein-DNA |
3
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
Accession |
GO Term |
GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0043565
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sequence-specific DNA binding
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR004827
Basic-leucine zipper domain
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PFAM |
PF00170
PF07716
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PRINTS |
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PIRSF |
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SMART |
SM00338
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TIGRFAMs |
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Modification |
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SwissProt |
Q10587
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PhosphoSite |
PhosphoSite-Q10587
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
7008
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UniGene |
Hs.614502
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RefSeq |
NP_001138870
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HUGO |
HGNC:11722
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OMIM |
188595
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CCDS |
CCDS46716
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HPRD |
01783
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IMGT |
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EMBL |
AK091916
AK314906
AL035659
BC039258
BC042476
BX537848
CH471095
CR456592
CR541827
U06935
U44059
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GenPept |
AAA81373
AAB06497
AAH39258
AAH42476
BAG37419
BAG52441
CAD97856
CAG30478
CAG46626
CAI23516
CAQ08872
EAW60430
EAW60431
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