Version 5.4
Homo sapiens Protein: GLS
Summary
InnateDB Protein IDBP-293295.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GLS
Protein Name glutaminase
Synonyms AAD20; GAC; GAM; GLS1; KGA;
Species Homo sapiens
Ensembl Protein ENSP00000387177
InnateDB Gene IDBG-77587 (GLS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 13 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004359 glutaminase activity
GO:0005515 protein binding
Biological Process
GO:0006541 glutamine metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002110 Ankyrin repeat
IPR012338 Beta-lactamase/transpeptidase-like
IPR015868 Glutaminase
IPR020683 Ankyrin repeat-containing domain
PFAM PF00023
PF13606
PF04960
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B7Z509
UniProt Splice Variant
Entrez Gene 2744
UniGene Hs.707400
RefSeq
HUGO HGNC:4331
OMIM 138280
CCDS
HPRD 00700
IMGT
EMBL AC005540 AC067945 AC079162 AK298266
GenPept BAH12745

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca