Version 5.4
Homo sapiens Protein: ZNF385B
Summary
InnateDB Protein IDBP-293414.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF385B
Protein Name zinc finger protein 385B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000386845
InnateDB Gene IDBG-76625 (ZNF385B)
Protein Structure
UniProt Annotation
Function May play a role in p53/TP53-mediated apoptosis. {ECO:0000269PubMed:22945289}.
Subcellular Localization Nucleus {ECO:0000269PubMed:22945289}.
Disease Associations
Tissue Specificity Detected in germinal center of lymph node (at protein level). Expressed in spleen, lymph node and tonsil. {ECO:0000269PubMed:22945289}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR003604 Zinc finger, U1-type
IPR015880 Zinc finger, C2H2-like
IPR022755 Zinc finger, double-stranded RNA binding
PFAM PF12171
PRINTS
PIRSF
SMART SM00451
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q569K4
PhosphoSite PhosphoSite-Q569K4
TrEMBL Q53S82
UniProt Splice Variant
Entrez Gene 151126
UniGene Hs.655005
RefSeq NP_689733
HUGO HGNC:26332
OMIM 612344
CCDS CCDS33339
HPRD 15823
IMGT
EMBL AC062033 AC068042 AC092642 AC093604 AK057999 AK096822 AK131432 BC038422 BC048123 BC092423
GenPept AAH38422 AAH48123 AAH92423 AAY24322 AAY24346 BAB71629 BAC04870 BAD18578

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca