Version 5.4
Homo sapiens Protein: EXD2
Summary
InnateDB Protein IDBP-293442.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EXD2
Protein Name exonuclease 3'-5' domain containing 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000386839
InnateDB Gene IDBG-10327 (EXD2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002562 3\'-5\' exonuclease domain
IPR012337 Ribonuclease H-like domain
PFAM PF01612
PRINTS
PIRSF
SMART SM00474
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NVH0
PhosphoSite PhosphoSite-Q9NVH0
TrEMBL C9JLF4
UniProt Splice Variant
Entrez Gene 55218
UniGene Hs.533878
RefSeq XP_005267875
HUGO HGNC:20217
OMIM
CCDS CCDS9793
HPRD 16592
IMGT
EMBL AK001600 AK295601 AL359317 AL834434 BC001962 BX647767 CH471061
GenPept AAH01962 BAA91781 BAG58488 CAD39094 CAH10568 EAW80985

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca