Homo sapiens Protein: HOXD12
Summary
InnateDB Protein IDBP-293523.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HOXD12
Protein Name homeobox D12
Synonyms HOX4H;
Species Homo sapiens
Ensembl Protein ENSP00000385586
InnateDB Gene IDBG-75675 (HOXD12)
Protein Structure
UniProt Annotation
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001501 skeletal system development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007389 pattern specification process
GO:0042733 embryonic digit morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa
PFAM PF00046
PRINTS PR00024
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P35452
PhosphoSite PhosphoSite-P35452
TrEMBL
UniProt Splice Variant
Entrez Gene 3238
UniGene
RefSeq NP_067016
HUGO HGNC:5135
OMIM 142988
CCDS CCDS46456
HPRD 00871
IMGT
EMBL AC009336 AF154915 CH471058
GenPept AAF79044 EAX11094