Version 5.4
Homo sapiens Protein: CAMKMT
Summary
InnateDB Protein IDBP-293671.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAMKMT
Protein Name calmodulin-lysine N-methyltransferase
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000385124
InnateDB Gene IDBG-49878 (CAMKMT)
Protein Structure
UniProt Annotation
Function Catalyzes the trimethylation of 'Lys-116' in calmodulin. {ECO:0000269PubMed:20975703}.
Subcellular Localization Isoform 1: Cytoplasm. Nucleus.Isoform 2: Golgi apparatus.
Disease Associations
Tissue Specificity Isoform 1 is expressed in brain,liver, muscle colon and lung. Isoform 2 is expressed in colon, testis, kidney and brain. Isoform 1 and isoform 2 are expressed in normal lymphoblastoid cells but not in lymphoblastoid cells from patients with hypotonia-cystinuria syndrome. {ECO:0000269PubMed:15913950}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0018025 calmodulin-lysine N-methyltransferase activity
Biological Process
GO:0018022 peptidyl-lysine methylation
Cellular Component
GO:0005634 nucleus
GO:0005794 Golgi apparatus
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7Z624
PhosphoSite PhosphoSite-Q7Z624
TrEMBL
UniProt Splice Variant
Entrez Gene 79823
UniGene Hs.677439
RefSeq
HUGO HGNC:26276
OMIM 609559
CCDS
HPRD 08028
IMGT
EMBL AC016703 AC067957 AK027104 BC029359 BC053733
GenPept AAH29359 AAH53733 AAX88866 AAX93163 BAB15658

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca