InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: METTL5

Summary

InnateDB Protein

IDBP-293685.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

METTL5

Protein Name

methyltransferase like 5

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000386703

InnateDB Gene

IDBG-74599 (METTL5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0008168	methyltransferase activity
GO:0008276	protein methyltransferase activity

Biological Process

GO:0001510	RNA methylation
GO:0006479	protein methylation
GO:0008152	metabolic process
GO:0009452	7-methylguanosine RNA capping
GO:0031167	rRNA methylation
GO:0032259	methylation

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000241 Putative RNA methylase domain
IPR004398 RNA methyltransferase, RsmD
IPR007848 Methyltransferase small domain
IPR010456 Ribosomal L11 methyltransferase, PrmA
IPR013216 Methyltransferase type 11
IPR019012 RNA cap guanine-N2 methyltransferase
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF01170
PF03602
PF05175
PF06325
PF08241
PF09445

PRINTS

PIRSF

PIRSF004553

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

B8ZZE3

UniProt Splice Variant

Entrez Gene

29081

UniGene

RefSeq

HUGO

HGNC:25006

OMIM

CCDS

HPRD

IMGT

EMBL

AC009967 CH471058

GenPept

EAX11253