Version 5.4
Homo sapiens Protein: XIRP2
Summary
InnateDB Protein IDBP-293774.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol XIRP2
Protein Name xin actin-binding repeat containing 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000386619
InnateDB Gene IDBG-74247 (XIRP2)
Protein Structure
UniProt Annotation
Function Protects actin filaments from depolymerization. {ECO:0000269PubMed:15454575}.
Subcellular Localization Cell junction {ECO:0000269PubMed:15454575}. Note=Colocalizes with actin stress fibers. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0008270 zinc ion binding
Biological Process
GO:0030036 actin cytoskeleton organization
Cellular Component
GO:0030054 cell junction
Protein Structure and Domains
PDB ID
InterPro IPR001781 Zinc finger, LIM-type
PFAM PF00412
PRINTS
PIRSF
SMART SM00132
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A4UGR9
PhosphoSite PhosphoSite-A4UGR9
TrEMBL
UniProt Splice Variant
Entrez Gene 129446
UniGene Hs.73680
RefSeq NP_001186072
HUGO HGNC:14303
OMIM 609778
CCDS CCDS56143
HPRD 10267
IMGT
EMBL AC092601 AC093684 AC108494 AC133782 AJ626901 AK096430 AK122889 AL831970 AL831985 AL832011 AL832331 AL832336 AL832360 AL832382 AL832452 AL833291 AY820969 BC018673 BC022888 CH471058 EF119711 EF119717 EF119718 EF119719 EF119720 EF119721 EF119722
GenPept AAH18673 AAV87913 AAY24138 ABO69245 ABO69246 ABO69247 ABO69248 ABO69249 ABO69250 ABO69251 BAG53782 CAD38624 CAD89919 CAD89958 CAD91137 CAD91139 CAD91141 CAD91146 CAD91154 CAD91156 CAF25193 EAX11311

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca