Version 5.4
Homo sapiens Protein: THADA
Summary
InnateDB Protein IDBP-293795.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol THADA
Protein Name thyroid adenoma associated
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000386088
InnateDB Gene IDBG-48767 (THADA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations Note=Chromosomal aberrations involving THADA have been observed in benign thyroid adenomas. Translocation t(2;3)(p21;p25) and translocation t(2;7)(p21;p15); the sequences derived from chromosomes 3p25 and 7p15 do not appear to include a coding region and the fusion events probably result in truncated THADA proteins.
Tissue Specificity Expressed in pancreas, adrenal medulla, thyroid, adrenal cortex, testis, thymus, small intestine and stomach. {ECO:0000269PubMed:12955091}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR016024 Armadillo-type fold
IPR019442 Domain of unknown function DUF2428, death-receptor-like
PFAM PF10350
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6YHU6
PhosphoSite PhosphoSite-Q6YHU6
TrEMBL Q6YHU4
UniProt Splice Variant
Entrez Gene 63892
UniGene Hs.369592
RefSeq NP_071348
HUGO HGNC:19217
OMIM 611800
CCDS CCDS46268
HPRD 18177
IMGT
EMBL AB051554 AC010883 AC092615 AC092838 AC104138 AF323176 AK025445 AK025530 AK126004 AK290023 AY149629 AY149631 AY149633 BC007743 BC025773 BC037990 BC105976
GenPept AAH07743 AAH25773 AAH37990 AAI05977 AAK11318 AAO46785 AAO46787 AAO46789 AAX93152 AAX93154 AAY14994 BAB15133 BAB15162 BAB21858 BAC86389 BAF82712

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca