InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CD160

Summary

InnateDB Protein

IDBP-293850.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CD160

Protein Name

CD160 molecule

Synonyms

BY55; NK1; NK28;

Species

Homo sapiens

Ensembl Protein

ENSP00000385199

InnateDB Gene

IDBG-101772 (CD160)

Protein Structure

UniProt Annotation

Function

Receptor showing broad specificity for both classical and non-classical MHC class I molecules. {ECO:0000269PubMed:9973372}.

Subcellular Localization

Cell membrane; Lipid-anchor, GPI-anchor.

Disease Associations

Tissue Specificity

Expressed in spleen, peripheral blood, and small intestine. Expression is restricted to functional NK and T cytotoxic lymphocytes.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005102	receptor binding
GO:0032393	MHC class I receptor activity

Biological Process

GO:0006968	cellular defense response
GO:0007166	cell surface receptor signaling pathway
GO:0008283	cell proliferation
GO:0050776	regulation of immune response

Cellular Component

GO:0005886	plasma membrane
GO:0046658	anchored component of plasma membrane

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O95971

PhosphoSite

PhosphoSite-O95971

TrEMBL

B8PRF2

UniProt Splice Variant

Entrez Gene

11126

UniGene

Hs.740780

RefSeq

XP_005272986

HUGO

HGNC:17013

OMIM

604463

CCDS

HPRD

06833

IMGT

EMBL

AF060981 BC014465 EU016100

GenPept

AAC72302 AAH14465 ABV89736