InnateDB Protein
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IDBP-293973.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TAS2R41
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Protein Name
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taste receptor, type 2, member 41
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000386201
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InnateDB Gene
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IDBG-281704 (TAS2R41)
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Protein Structure
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Function |
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). {ECO:0000250}.
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Subcellular Localization |
Membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
Accession |
GO Term |
GO:0004930
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G-protein coupled receptor activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007960
Mammalian taste receptor
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PFAM |
PF05296
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P59536
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PhosphoSite |
PhosphoSite-P59536
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
259287
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UniGene |
Hs.650648
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RefSeq |
NP_795364
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HUGO |
HGNC:18883
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OMIM |
613965
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CCDS |
CCDS43663
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HPRD |
18151
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IMGT |
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EMBL |
AB199177
AB199178
AB199179
AC073264
AF494232
AY114093
AY724956
BC101157
BC101158
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GenPept |
AAI01158
AAI01159
AAM19323
AAM63543
AAU21152
BAD98051
BAD98052
BAD98053
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