Homo sapiens Protein: FAT3
Summary
InnateDB Protein IDBP-294139.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAT3
Protein Name FAT tumor suppressor homolog 3 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000387040
InnateDB Gene IDBG-67775 (FAT3)
Protein Structure
UniProt Annotation
Function May play a role in the interactions between neurites derived from specific subsets of neurons during development. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate. {ECO:0000269PubMed:16865240}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0007156 homophilic cell adhesion
GO:0007275 multicellular organismal development
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000742 Epidermal growth factor-like domain
IPR001791 Laminin G domain
IPR001881 EGF-like calcium-binding domain
IPR002126 Cadherin
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR015919 Cadherin-like
PFAM PF00008
PF00054
PF02210
PF07645
PF00028
PRINTS PR00205
PIRSF
SMART SM00181
SM00210
SM00282
SM00179
SM00112
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TDW7
PhosphoSite PhosphoSite-Q8TDW7
TrEMBL G5EA25
UniProt Splice Variant
Entrez Gene 120114
UniGene Hs.98523
RefSeq NP_001008781
HUGO HGNC:23112
OMIM 612483
CCDS
HPRD
IMGT
EMBL AB076400 AP000722 AP000805 AP002514 AP003171 AP003718 BC016722 CH471065
GenPept AAH16722 BAB86868 EAW66886