Version 5.4
Homo sapiens Protein: HMSD
Summary
InnateDB Protein IDBP-294245.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HMSD
Protein Name histocompatibility (minor) serpin domain containing
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000386207
InnateDB Gene IDBG-281549 (HMSD)
Protein Structure
UniProt Annotation
Function Putative serine protease inhibitor. {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Highly expressed in dendritic cells and primary leukemia cells, especially those of myeloid lineage. {ECO:0000269PubMed:17409267}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR023796 Serpin domain
PFAM PF00079
PRINTS
PIRSF
SMART SM00093
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A8MTL9
PhosphoSite PhosphoSite-A8MTL9
TrEMBL
UniProt Splice Variant
Entrez Gene 284293
UniGene Hs.735470
RefSeq NP_001116838
HUGO HGNC:23037
OMIM 612086
CCDS CCDS42441
HPRD
IMGT
EMBL AC009802 AW205887 BM696260 CH471096
GenPept EAW63164

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca