Version 5.4
Homo sapiens Protein: KCNF1
Summary
InnateDB Protein IDBP-29439.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNF1
Protein Name potassium voltage-gated channel, subfamily F, member 1
Synonyms IK8; KCNF; kH1; KV5.1;
Species Homo sapiens
Ensembl Protein ENSP00000295082
InnateDB Gene IDBG-29435 (KCNF1)
Protein Structure
UniProt Annotation
Function Putative voltage-gated potassium channel.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Detected in heart, brain, liver, skeletal muscle, kidney and pancreas.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005267 potassium channel activity
Biological Process
GO:0006811 ion transport
GO:0006813 potassium ion transport
GO:0007268 synaptic transmission
GO:0034765 regulation of ion transmembrane transport
GO:0051260 protein homooligomerization
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR003091 Potassium channel
IPR003131 Potassium channel tetramerisation-type BTB domain
IPR003968 Potassium channel, voltage dependent, Kv
IPR003969 Potassium channel, voltage dependent, Kv6
IPR003971 Potassium channel, voltage dependent, Kv9
IPR003972 Potassium channel, voltage dependent, Kv1
IPR005821 Ion transport domain
IPR011333 BTB/POZ fold
IPR013099 Two pore domain potassium channel domain
IPR013122 Polycystin cation channel, PKD1/PKD2
PFAM PF02214
PF00520
PF07885
PF08016
PRINTS PR00169
PR01491
PR01492
PR01494
PR01496
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H3M0
PhosphoSite PhosphoSite-Q9H3M0
TrEMBL
UniProt Splice Variant
Entrez Gene 3754
UniGene Hs.23735
RefSeq NP_002227
HUGO HGNC:6246
OMIM 603787
CCDS CCDS1676
HPRD 04808
IMGT
EMBL AC019041 AF029780 AF033382 BC026110 CH471053
GenPept AAC05597 AAG43055 AAH26110 AAX81991 EAX00946

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca