InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: AQP1

Summary

InnateDB Protein

IDBP-294461.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AQP1

Protein Name

aquaporin 1 (Colton blood group)

Synonyms

AQP-CHIP; CHIP28; CO;

Species

Homo sapiens

Ensembl Protein

ENSP00000386712

InnateDB Gene

IDBG-407455 (AQP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 42 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	42 [view]
Protein-Protein	42 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005223	intracellular cGMP activated cation channel activity
GO:0005267	potassium channel activity
GO:0005372	water transmembrane transporter activity
GO:0005515	protein binding
GO:0008519	ammonium transmembrane transporter activity
GO:0015079	potassium ion transmembrane transporter activity
GO:0015168	glycerol transmembrane transporter activity
GO:0015250	water channel activity
GO:0022857	transmembrane transporter activity
GO:0030184	nitric oxide transmembrane transporter activity
GO:0035379	carbon dioxide transmembrane transporter activity

Biological Process

GO:0003097	renal water transport
GO:0006182	cGMP biosynthetic process
GO:0006810	transport
GO:0006813	potassium ion transport
GO:0006833	water transport
GO:0006884	cell volume homeostasis
GO:0015670	carbon dioxide transport
GO:0015696	ammonium transport
GO:0015701	bicarbonate transport
GO:0015793	glycerol transport
GO:0019725	cellular homeostasis
GO:0021670	lateral ventricle development
GO:0030157	pancreatic juice secretion
GO:0030185	nitric oxide transport
GO:0030950	establishment or maintenance of actin cytoskeleton polarity
GO:0033326	cerebrospinal fluid secretion
GO:0033554	cellular response to stress
GO:0034644	cellular response to UV
GO:0035377	transepithelial water transport
GO:0035378	carbon dioxide transmembrane transport
GO:0042476	odontogenesis
GO:0042493	response to drug
GO:0043066	negative regulation of apoptotic process
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044281	small molecule metabolic process
GO:0045766	positive regulation of angiogenesis
GO:0046878	positive regulation of saliva secretion
GO:0048146	positive regulation of fibroblast proliferation
GO:0050891	multicellular organismal water homeostasis
GO:0055085	transmembrane transport
GO:0070301	cellular response to hydrogen peroxide
GO:0071241	cellular response to inorganic substance
GO:0071260	cellular response to mechanical stimulus
GO:0071280	cellular response to copper ion
GO:0071288	cellular response to mercury ion
GO:0071300	cellular response to retinoic acid
GO:0071320	cellular response to cAMP
GO:0071456	cellular response to hypoxia
GO:0071472	cellular response to salt stress
GO:0071474	cellular hyperosmotic response
GO:0071549	cellular response to dexamethasone stimulus
GO:0071732	cellular response to nitric oxide
GO:0071805	potassium ion transmembrane transport
GO:0072488	ammonium transmembrane transport
GO:0085018	maintenance of symbiont-containing vacuole by host

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0005903	brush border
GO:0009925	basal plasma membrane
GO:0016020	membrane
GO:0016323	basolateral plasma membrane
GO:0016324	apical plasma membrane
GO:0020003	symbiont-containing vacuole
GO:0020005	symbiont-containing vacuole membrane
GO:0031526	brush border membrane
GO:0031965	nuclear membrane
GO:0042383	sarcolemma
GO:0045177	apical part of cell
GO:0070062	extracellular vesicular exosome