Version 5.4
Homo sapiens Protein: ABCB5
Summary
InnateDB Protein IDBP-294994.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABCB5
Protein Name ATP-binding cassette, sub-family B (MDR/TAP), member 5
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000384881
InnateDB Gene IDBG-9209 (ABCB5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0015562 efflux transmembrane transporter activity
GO:0016887 ATPase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Biological Process
GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
GO:0002591 positive regulation of antigen processing and presentation of peptide antigen via MHC class I
GO:0006200 ATP catabolic process
GO:0006810 transport
GO:0042391 regulation of membrane potential
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR001140 ABC transporter, transmembrane domain
IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR011527 ABC transporter type 1, transmembrane domain
IPR019195 ABC transporter, ATPase, putative
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00664
PF13748
PF00005
PF09818
PRINTS
PIRSF
SMART SM00382
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2M3G0
PhosphoSite PhosphoSite-Q2M3G0
TrEMBL
UniProt Splice Variant
Entrez Gene 340273
UniGene Hs.404102
RefSeq NP_001157413
HUGO HGNC:46
OMIM 611785
CCDS CCDS55090
HPRD
IMGT
EMBL AB353947 AC002486 AC005060 AF319622 AF399931 AY090613 AY230001 AY234788 AY851364 AY851365 BC104894 BC104920 BC110370 CH236948 CH471073 GU437216
GenPept AAI04895 AAI04921 AAM09027 AAN76500 AAO73470 AAP55848 AAQ03033 AAW31629 AAW31630 ADV32636 BAF75364 EAL24273 EAW93726

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca