Homo sapiens Protein: A2M
Summary
InnateDB Protein IDBP-295008.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol A2M
Protein Name alpha-2-macroglobulin
Synonyms A2MD; CPAMD5; FWP007; S863-7;
Species Homo sapiens
Ensembl Protein ENSP00000385710
InnateDB Gene IDBG-17623 (A2M)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 138 experimentally validated interaction(s) in this database.
Experimentally validated
Total 138 [view]
Protein-Protein 138 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004866 endopeptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002890 Alpha-2-macroglobulin, N-terminal
IPR008972 Cupredoxin
PFAM PF01835
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F8W7L3
UniProt Splice Variant
Entrez Gene 2
UniGene Hs.212838
RefSeq
HUGO HGNC:7
OMIM 103950
CCDS
HPRD 00072
IMGT
EMBL AC007436
GenPept