InnateDB Protein
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IDBP-295090.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ORAI2
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Protein Name
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ORAI calcium release-activated calcium modulator 2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000385489
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InnateDB Gene
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IDBG-33563 (ORAI2)
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Protein Structure
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Function |
Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)- selective current by synergy with the Ca(2+) sensor, STIM1. {ECO:0000269PubMed:16807233, ECO:0000269PubMed:17452328}.
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Subcellular Localization |
Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
7
[view]
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Protein-Protein |
7
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR012446
Calcium release-activated calcium channel protein
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PFAM |
PF07856
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q96SN7
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PhosphoSite |
PhosphoSite-Q96SN7
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TrEMBL |
C9JUY6
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UniProt Splice Variant |
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Entrez Gene |
80228
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UniGene |
Hs.363308
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RefSeq |
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HUGO |
HGNC:21667
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OMIM |
610929
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CCDS |
CCDS5722
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HPRD |
09860
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IMGT |
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EMBL |
AC093668
AF258552
AK027639
AK300574
BC069270
CH471197
CR457287
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GenPept |
AAG23755
AAH69270
AAP22351
AAP22352
BAB55256
BAG62276
CAG33568
EAW50244
EAW50245
EAW50247
EAW50248
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