Version 5.4
| Homo sapiens Protein: LIPM | |||||
|---|---|---|---|---|---|
| Summary | |||||
| InnateDB Protein | IDBP-295263.5 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | LIPM | ||||
| Protein Name | lipase, family member M | ||||
| Synonyms | |||||
| Species | Homo sapiens | ||||
| Ensembl Protein | ENSP00000383901 | ||||
| InnateDB Gene | IDBG-81541 (LIPM) | ||||
| Protein Structure |
|
||||
| UniProt Annotation | |||||
| Function | Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers. {ECO:0000269PubMed:17562024}. | ||||
| Subcellular Localization | Secreted {ECO:0000305}. | ||||
| Disease Associations | |||||
| Tissue Specificity | Exclusively expressed in the epidermis within the granular keratinocytes. {ECO:0000269PubMed:17562024}. | ||||
| Comments | |||||
| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||||
| Gene Ontology | |||||
Molecular Function |
|
||||
| Biological Process |
|
||||
| Cellular Component |
|
||||
| Protein Structure and Domains | |||||
| PDB ID | |||||
| InterPro |
IPR000073
Alpha/beta hydrolase fold-1 IPR006693 Partial AB-hydrolase lipase domain IPR029058 Alpha/Beta hydrolase fold |
||||
| PFAM |
PF00561
PF04083 |
||||
| PRINTS |
PR00111
|
||||
| PIRSF | |||||
| SMART | |||||
| TIGRFAMs | |||||
| Post-translational Modifications | |||||
| Modification | |||||
| Cross-References | |||||
| SwissProt | Q5VYY2 | ||||
| PhosphoSite | PhosphoSite-Q5VYY2 | ||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | 340654 | ||||
| UniGene | Hs.55118 | ||||
| RefSeq | NP_001121687 | ||||
| HUGO | HGNC:23455 | ||||
| OMIM | 613923 | ||||
| CCDS | CCDS44457 | ||||
| HPRD | |||||
| IMGT | |||||
| EMBL | AL353113 AL358532 EF426484 | ||||
| GenPept | ABR08389 CAH72238 CAO77925 | ||||