Version 5.4
| Homo sapiens Protein: LIPK | |||||
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| Summary | |||||
| InnateDB Protein | IDBP-295269.5 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | LIPK | ||||
| Protein Name | lipase, family member K | ||||
| Synonyms | |||||
| Species | Homo sapiens | ||||
| Ensembl Protein | ENSP00000383900 | ||||
| InnateDB Gene | IDBG-81530 (LIPK) | ||||
| Protein Structure |
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| UniProt Annotation | |||||
| Function | Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers. {ECO:0000269PubMed:17562024}. | ||||
| Subcellular Localization | Secreted {ECO:0000305}. | ||||
| Disease Associations | |||||
| Tissue Specificity | Exclusively expressed in the epidermis within the granular keratinocytes. {ECO:0000269PubMed:17562024}. | ||||
| Comments | |||||
| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||
| PDB ID | |||||
| InterPro |
IPR000073
Alpha/beta hydrolase fold-1 IPR006693 Partial AB-hydrolase lipase domain IPR029058 Alpha/Beta hydrolase fold |
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| PFAM |
PF00561
PF04083 |
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| PRINTS |
PR00111
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| PIRSF | |||||
| SMART | |||||
| TIGRFAMs | |||||
| Post-translational Modifications | |||||
| Modification | |||||
| Cross-References | |||||
| SwissProt | Q5VXJ0 | ||||
| PhosphoSite | PhosphoSite-Q5VXJ0 | ||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | 643414 | ||||
| UniGene | Hs.632092 | ||||
| RefSeq | NP_001073987 | ||||
| HUGO | HGNC:23444 | ||||
| OMIM | 613922 | ||||
| CCDS | CCDS44455 | ||||
| HPRD | |||||
| IMGT | |||||
| EMBL | AL358532 EF426482 | ||||
| GenPept | ABR08387 CAH71058 | ||||