Version 5.4
Homo sapiens Protein: PLGLB2
Summary
InnateDB Protein IDBP-295300.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLGLB2
Protein Name plasminogen-like B2
Synonyms PLGL; PLGP1; PRGB; PRP-B;
Species Homo sapiens
Ensembl Protein ENSP00000386317
InnateDB Gene IDBG-60277 (PLGLB2)
Protein Structure
UniProt Annotation
Function May bind noncovalently to lysine binding sites present in the kringle structures of plasminogen. This may interfere with the binding of fibrin or alpha-2-antiplasmin to plasminogen and may result in the localization of activity at sites necessary for extracellular matrix destruction.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 0
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR003014 PAN-1 domain
IPR003609 Apple-like
PFAM PF00024
PRINTS
PIRSF
SMART SM00473
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q02325
PhosphoSite PhosphoSite-Q02325
TrEMBL Q53QL7
UniProt Splice Variant
Entrez Gene 5343
UniGene
RefSeq
HUGO HGNC:9073
OMIM 173340
CCDS CCDS1999
HPRD 01416
IMGT
EMBL AC093616 AC111200 BC005379 BC022294 BC109248 M86874 M86875 M86876 M93143
GenPept AAA60169 AAB06491 AAH05379 AAH22294 AAI09249 AAX82025 AAY24020

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca