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InnateDB Protein
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IDBP-295530.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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MTHFD2
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Protein Name
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methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
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Synonyms
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NMDMC;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000386536
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InnateDB Gene
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IDBG-57007 (MTHFD2)
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Protein Structure
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| Function |
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
11
[view]
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| Protein-Protein |
11
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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Molecular Function |
| Accession |
GO Term |
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GO:0003824
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catalytic activity
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GO:0004488
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methylenetetrahydrofolate dehydrogenase (NADP+) activity
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| Biological Process |
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GO:0009396
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folic acid-containing compound biosynthetic process
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GO:0055114
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oxidation-reduction process
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR020630
Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
IPR020631
Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
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| PFAM |
PF00763
PF02882
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
B9A062
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| UniProt Splice Variant |
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| Entrez Gene |
10797
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| UniGene |
Hs.697648
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| RefSeq |
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| HUGO |
HGNC:7434
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| OMIM |
604887
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| CCDS |
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| HPRD |
05351
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| IMGT |
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| EMBL |
AC073263
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| GenPept |
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Version 5.4