Version 5.4
Homo sapiens Protein: TBC1D2B
Summary
InnateDB Protein IDBP-295678.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBC1D2B
Protein Name TBC1 domain family, member 2B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000387165
InnateDB Gene IDBG-24382 (TBC1D2B)
Protein Structure
UniProt Annotation
Function May act as a GTPase-activating protein. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005097 Rab GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0032313 regulation of Rab GTPase activity
GO:0032851 positive regulation of Rab GTPase activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000195 Rab-GTPase-TBC domain
IPR001849 Pleckstrin homology domain
IPR009053 Prefoldin
PFAM PF00566
PF00169
PRINTS
PIRSF
SMART SM00164
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UPU7
PhosphoSite PhosphoSite-Q9UPU7
TrEMBL
UniProt Splice Variant
Entrez Gene 23102
UniGene Hs.658248
RefSeq NP_055894
HUGO HGNC:29183
OMIM
CCDS CCDS32301
HPRD 08310
IMGT
EMBL AB028978 AC090260 AC104758 AK000173 BC033712 BC152465 CH471136
GenPept AAH33712 AAI52466 BAA83007 BAA90990 EAW99188 EAW99190

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca