InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RCVRN

Summary

InnateDB Protein

IDBP-29944.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RCVRN

Protein Name

recoverin

Synonyms

RCV1;

Species

Homo sapiens

Ensembl Protein

ENSP00000226193

InnateDB Gene

IDBG-29942 (RCVRN)

Protein Structure

UniProt Annotation

Function

Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.

Subcellular Localization

Disease Associations

Tissue Specificity

Retina and pineal gland.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0008048	calcium sensitive guanylate cyclase activator activity

Biological Process

GO:0007165	signal transduction
GO:0007601	visual perception
GO:0007602	phototransduction
GO:0007603	phototransduction, visible light
GO:0016056	rhodopsin mediated signaling pathway
GO:0022400	regulation of rhodopsin mediated signaling pathway
GO:0031284	positive regulation of guanylate cyclase activity
GO:0051924	regulation of calcium ion transport