InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DNAH9

Summary

InnateDB Protein

IDBP-30768.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DNAH9

Protein Name

dynein, axonemal, heavy chain 9

Synonyms

DNAH17L; Dnahc9; DNEL1; DYH9; HL-20; HL20;

Species

Homo sapiens

Ensembl Protein

ENSP00000262442

InnateDB Gene

IDBG-30766 (DNAH9)

Protein Structure

UniProt Annotation

Function

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.

Subcellular Localization

Cytoplasm, cytoskeleton, cilium axoneme.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003774	motor activity
GO:0003777	microtubule motor activity
GO:0005524	ATP binding
GO:0016887	ATPase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0006928	cellular component movement
GO:0007018	microtubule-based movement
GO:0007283	spermatogenesis
GO:0008152	metabolic process
GO:0030030	cell projection organization

Cellular Component

GO:0005856	cytoskeleton
GO:0005874	microtubule
GO:0005930	axoneme
GO:0030286	dynein complex

Protein Structure and Domains

PDB ID

InterPro

IPR003593 AAA+ ATPase domain
IPR004273 Dynein heavy chain domain
IPR011704 ATPase, dynein-related, AAA domain
IPR013594 Dynein heavy chain, domain-1
IPR013602 Dynein heavy chain, domain-2
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF03028
PF07728
PF08385
PF08393

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9NYC9