Homo sapiens Protein: PRSS50
Summary
InnateDB Protein IDBP-30820.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRSS50
Protein Name protease, serine, 50
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000326598
InnateDB Gene IDBG-30818 (PRSS50)
Protein Structure
UniProt Annotation
Function May be involved in proteolysis through its threonine endopeptidase activity. {ECO:0000269PubMed:17283160}.
Subcellular Localization Endoplasmic reticulum {ECO:0000305PubMed:17283160}. Note=May also localize to cytoplasmic membranes.
Disease Associations
Tissue Specificity Testis specific. Differentially expressed in some breast cancer tissues.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0004298 threonine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
Protein Structure and Domains
PDB ID
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR015420 Peptidase S1A, nudel
PFAM PF00089
PF09342
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UI38
PhosphoSite PhosphoSite-Q9UI38
TrEMBL B3KUP4
UniProt Splice Variant
Entrez Gene 29122
UniGene Hs.120365
RefSeq NP_037402
HUGO HGNC:17910
OMIM 607950
CCDS CCDS2745
HPRD 06405
IMGT
EMBL AF100707 AK097666 BC033016 BC037775
GenPept AAF22500 AAH33016 AAH37775 BAG53506