InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GPC2

Summary

InnateDB Protein

IDBP-30825.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GPC2

Protein Name

glypican 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000292377

InnateDB Gene

IDBG-242431 (GPC2)

Protein Structure

UniProt Annotation

Function

Cell surface proteoglycan that bears heparan sulfate. May fulfill a function related to the motile behaviors of developing neurons (By similarity). {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}; Extracellular side {ECO:0000250}.Secreted glypican-2: Secreted, extracellular space {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0043395	heparan sulfate proteoglycan binding

Biological Process

GO:0001523	retinoid metabolic process
GO:0005975	carbohydrate metabolic process
GO:0006024	glycosaminoglycan biosynthetic process
GO:0006027	glycosaminoglycan catabolic process
GO:0007224	smoothened signaling pathway
GO:0007603	phototransduction, visible light
GO:0030182	neuron differentiation
GO:0030203	glycosaminoglycan metabolic process
GO:0030204	chondroitin sulfate metabolic process
GO:0044281	small molecule metabolic process

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0005615	extracellular space
GO:0005783	endoplasmic reticulum
GO:0005796	Golgi lumen
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0031225	anchored component of membrane
GO:0043202	lysosomal lumen