Version 5.4
Homo sapiens Protein: RNF141
Summary
InnateDB Protein IDBP-31739.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNF141
Protein Name ring finger protein 141
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000265981
InnateDB Gene IDBG-31737 (RNF141)
Protein Structure
UniProt Annotation
Function May be involved in spermatogenesis. {ECO:0000269PubMed:11672448}.
Subcellular Localization
Disease Associations
Tissue Specificity Isoform 1 is testis-specific. Isoform 2 is expressed in heart, brain, skeletal muscle, kidney and pancreas. Isoform 1 is not expressed in fetus or in azoospermic patients. {ECO:0000269PubMed:11672448}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0051865 protein autoubiquitination
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001841 Zinc finger, RING-type
IPR018957 Zinc finger, C3HC4 RING-type
PFAM PF13639
PF14634
PF00097
PRINTS
PIRSF
SMART SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WVD5
PhosphoSite PhosphoSite-Q8WVD5
TrEMBL E9PQV2
UniProt Splice Variant
Entrez Gene 50862
UniGene Hs.624085
RefSeq NP_057506
HUGO HGNC:21159
OMIM
CCDS CCDS7803
HPRD 11509
IMGT
EMBL AC021914 AF214680 AK289764 BC018104 BT006662 CH471064
GenPept AAF30180 AAH18104 AAP35308 BAF82453 EAW68566

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca