InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: OSR1

Summary

InnateDB Protein

IDBP-31777.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

OSR1

Protein Name

odd-skipped related 1 (Drosophila)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000272223

InnateDB Gene

IDBG-31773 (OSR1)

Protein Structure

UniProt Annotation

Function

Transcription factor that plays a role in the regulation of embryonic heart and urogenital development. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed in adult colon, small intestine, prostate, testis, and fetal lung. {ECO:0000269PubMed:12119563}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001655	urogenital system development
GO:0001656	metanephros development
GO:0001657	ureteric bud development
GO:0001823	mesonephros development
GO:0002062	chondrocyte differentiation
GO:0006351	transcription, DNA-templated
GO:0007507	heart development
GO:0008406	gonad development
GO:0010628	positive regulation of gene expression
GO:0030154	cell differentiation
GO:0030501	positive regulation of bone mineralization
GO:0030857	negative regulation of epithelial cell differentiation
GO:0035115	embryonic forelimb morphogenesis
GO:0035116	embryonic hindlimb morphogenesis
GO:0036023	embryonic skeletal limb joint morphogenesis
GO:0042474	middle ear morphogenesis
GO:0042476	odontogenesis
GO:0042733	embryonic digit morphogenesis
GO:0043066	negative regulation of apoptotic process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048389	intermediate mesoderm development
GO:0048793	pronephros development
GO:0048863	stem cell differentiation
GO:0050679	positive regulation of epithelial cell proliferation
GO:0060021	palate development
GO:0060272	embryonic skeletal joint morphogenesis
GO:0071300	cellular response to retinoic acid
GO:0072075	metanephric mesenchyme development
GO:0072111	cell proliferation involved in kidney development
GO:0072133	metanephric mesenchyme morphogenesis
GO:0072143	mesangial cell development
GO:0072162	metanephric mesenchymal cell differentiation
GO:0072166	posterior mesonephric tubule development
GO:0072168	specification of anterior mesonephric tubule identity
GO:0072169	specification of posterior mesonephric tubule identity
GO:0072180	mesonephric duct morphogenesis
GO:0072183	negative regulation of nephron tubule epithelial cell differentiation
GO:0072184	renal vesicle progenitor cell differentiation
GO:0072190	ureter urothelium development
GO:0072207	metanephric epithelium development
GO:0072208	metanephric smooth muscle tissue development
GO:0072234	metanephric nephron tubule development
GO:0072239	metanephric glomerulus vasculature development
GO:0072259	metanephric interstitial cell development
GO:0072268	pattern specification involved in metanephros development
GO:0072498	embryonic skeletal joint development
GO:0090094	metanephric cap mesenchymal cell proliferation involved in metanephros development
GO:2000543	positive regulation of gastrulation