Homo sapiens Protein: ACOT12
Summary
InnateDB Protein IDBP-31848.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACOT12
Protein Name acyl-CoA thioesterase 12
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000303246
InnateDB Gene IDBG-31846 (ACOT12)
Protein Structure
UniProt Annotation
Function Hydrolyzes acetyl-CoA to acetate and CoA. {ECO:0000269PubMed:16951743}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:16951743}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003986 acetyl-CoA hydrolase activity
GO:0005524 ATP binding
GO:0008289 lipid binding
Biological Process
GO:0006084 acetyl-CoA metabolic process
GO:0006090 pyruvate metabolic process
GO:0006631 fatty acid metabolic process
GO:0006637 acyl-CoA metabolic process
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR002913 START domain
IPR006683 Thioesterase superfamily
IPR029069 HotDog domain
PFAM PF01852
PF03061
PRINTS
PIRSF
SMART SM00234
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WYK0
PhosphoSite PhosphoSite-Q8WYK0
TrEMBL
UniProt Splice Variant
Entrez Gene 134526
UniGene Hs.591756
RefSeq NP_570123
HUGO HGNC:24436
OMIM 614315
CCDS CCDS4055
HPRD 16680
IMGT
EMBL AB078619 AK122960 BC075010 BC075011 CH471084
GenPept AAH75010 AAH75011 BAB84022 BAG53821 EAW95875